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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HAPLN4 All Species: 13.64
Human Site: T87 Identified Species: 33.33
UniProt: Q86UW8 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.56
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UW8 NP_075378.1 402 42801 T87 D G V R L K W T K V V D P L A
Chimpanzee Pan troglodytes XP_524163 438 46405 T123 D G V R L K W T K V V D P L A
Rhesus Macaque Macaca mulatta XP_001115151 402 42936 T87 D G V R L K W T K V V D P L A
Dog Lupus familis XP_849484 354 40212 K83 K I R I K W T K L T S D Y L K
Cat Felis silvestris
Mouse Mus musculus Q80WM4 400 42790 T88 D G V R L K W T K V V D P L A
Rat Rattus norvegicus P03994 354 40243 K83 K I R I K W T K L T S D Y L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509283 354 40324 K83 K I R V K W T K L T S D Y L K
Chicken Gallus gallus P07354 355 40514 K84 K I R V K W T K L T S D Y L K
Frog Xenopus laevis NP_001079631 359 40867 K90 R H R V K W S K L H K D N T K
Zebra Danio Brachydanio rerio NP_001038372 344 39138 G67 E D V F V A L G R Q Q K A F G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.7 98.7 44 N.A. 91 43.7 N.A. 43.7 43.7 42 52.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 91.7 99 57.4 N.A. 92.7 57.4 N.A. 57.9 57.2 56.2 64.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 13.3 N.A. 100 13.3 N.A. 13.3 13.3 6.6 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 13.3 N.A. 13.3 13.3 6.6 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 0 0 0 0 0 0 10 0 40 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 40 10 0 0 0 0 0 0 0 0 0 90 0 0 0 % D
% Glu: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 40 0 0 0 0 0 10 0 0 0 0 0 0 10 % G
% His: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 0 40 0 20 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 40 0 0 0 50 40 0 50 40 0 10 10 0 0 40 % K
% Leu: 0 0 0 0 40 0 10 0 50 0 0 0 0 80 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % Q
% Arg: 10 0 50 40 0 0 0 0 10 0 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 10 0 0 0 40 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 40 40 0 40 0 0 0 10 0 % T
% Val: 0 0 50 30 10 0 0 0 0 40 40 0 0 0 0 % V
% Trp: 0 0 0 0 0 50 40 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _